CV

This Node Is Deprecated — This version of the node has been replaced with a new and improved version. The old version is kept for backwards-compatibility, but for all new workflows we suggest to use the version linked below.

Go to Suggested ReplacementCV

The CV is a statistical parameter that describes variance of data.

For each group of data (e.g. wells of plates) CVs are calculated for each selected subset (e.g. control wells of a plate).

CV = sd(x[subset] / mean(x[subset]) * 100
or
CV = mad(x[subset] / median(x[subset]) * 100

Literature: Zhang, J. et al., J Biomol Screen 1999; 4; 67
Wikipedia: Coefficient of variation

Options

Group wells by: Select the column to define the groups (e.g. "barcode" for plate-wise CVs).
Select subset column / well annotation column: Column with well annotations (e.g. treatment)
Choose subset(s) / well annotation(s): Select one or many subsets for which CVs are calculated (e.g. "negative control").
Use robust statistics: Median and mad will be calculated instead of mean and sd.
Include: Select the columns for which CVs will be calculated.

Input Ports

: Input table

Output Ports

: Table with CVs

Views

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Workflows

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Installation

To use this node in KNIME, install the extension KNIME HCS Tools from the below update site following our NodePit Product and Node Installation Guide:

v5.4

A zipped version of the software site can be downloaded here.

Plugin provider: Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

Plugin version: 5.4.0.v202412031157

On NodePit since: 2024-12-06

Last update: 2024-12-17

Tags: Deprecated

KNIME versions: v5.4, v5.3, v5.2, v5.1, v4.7, v4.6, v4.5, v4.4, v4.3, v4.2, v4.1, v4.0, v3.7, v3.6

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CV