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DeprecatedHCS-Tools for KNIME version 4.0.0.v202007151505 by Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)

The CV is a statistical parameter that describes variance of data.

For each group of data (e.g. wells of plates) CVs are calculated for each selected subset (e.g. control wells of a plate).

CV = sd(x[subset] / mean(x[subset]) * 100
CV = mad(x[subset] / median(x[subset]) * 100

Literature: Zhang, J. et al., J Biomol Screen 1999; 4; 67
Wikipedia: Coefficient of variation


Group wells by
Select the column to define the groups (e.g. "barcode" for plate-wise CVs).
Select subset column / well annotation column
Column with well annotations (e.g. treatment)
Choose subset(s) / well annotation(s)
Select one or many subsets for which CVs are calculated (e.g. "negative control").
Use robust statistics
Median and mad will be calculated instead of mean and sd.
Select the columns for which CVs will be calculated.

Input Ports

Input table

Output Ports

Table with CVs

Best Friends (Incoming)

Best Friends (Outgoing)



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