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Build antibody 2

Build Antibody Models

Several antibody models are built using Bioluminate starting from the heavy and light chain sequences.
Sequences can be read from an XLS spreadsheet. Post-translational modifications and protein descriptors are calculated for each model and the latter can be used as input to BioQSPR.

[Requires: Bioluminate]

Build Antibody Models: Several antibody models are built using Bioluminate starting from the heavy and light chain sequences.Sequences can be read from an XLS spreadsheet. Post-translational modifications and protein descriptors are calculated for each model and the latter can be usedas input to BioQSPR. [Requires: Bioluminate]Built models %file% 2 CPUs Numbering scheme,Number of models to build Input SequenceBioluminatebuild antibodyand Model IDas RowIDAntibodies Model inspection%file%all Model inspectioncalc_protein_descriptors.pyProtein descriptorsProperty listSettings:Numbering scheme,Number of models to build,PDB ID for fv template,Auto Fab option ScriptoptionsAggScoreAggregation scoreAll properties%file% To be used in BioQSPR for instanceProperties onlybuild_antibody.py Scriptoptions Reactive Residue Table xlsx2fasta.pyFilter by ExposurePost-translationalModifications Model inspection%file%Molecule Writer(from MAE) Chunk Loop Start Loop End ParallelChunk Start Parallel Chunk End Settings Preprocessing Input ChemistryExternal Tool Group Get PDB Postprocessing Run Maestro Molecule Writer(from MAE) Job Control Run Maestro Get Help ChemistryExternal Tool Table Viewer Build antibody Table Viewer Column Filter Table Viewer Table Viewer CSV Writer Column Filter Get Help Table Viewer Postprocessing Postprocessing Row Filter RowID Column Resorter ChemistryExternal Tool Excel Reader (XLS)(deprecated) Configuration Postprocessing Row Filter Table Viewer Run Maestro CSV Writer Build Antibody Models: Several antibody models are built using Bioluminate starting from the heavy and light chain sequences.Sequences can be read from an XLS spreadsheet. Post-translational modifications and protein descriptors are calculated for each model and the latter can be usedas input to BioQSPR. [Requires: Bioluminate]Built models %file% 2 CPUs Numbering scheme,Number of models to build Input SequenceBioluminatebuild antibodyand Model IDas RowIDAntibodies Model inspection%file%all Model inspectioncalc_protein_descriptors.pyProtein descriptorsProperty listSettings:Numbering scheme,Number of models to build,PDB ID for fv template,Auto Fab option ScriptoptionsAggScoreAggregation scoreAll properties%file% To be used in BioQSPR for instanceProperties onlybuild_antibody.py Scriptoptions Reactive Residue Table xlsx2fasta.pyFilter by ExposurePost-translationalModifications Model inspection%file%Molecule Writer(from MAE) Chunk Loop Start Loop End ParallelChunk Start Parallel Chunk End Settings Preprocessing Input ChemistryExternal Tool Group Get PDB Postprocessing Run Maestro Molecule Writer(from MAE) Job Control Run Maestro Get Help ChemistryExternal Tool Table Viewer Build antibody Table Viewer Column Filter Table Viewer Table Viewer CSV Writer Column Filter Get Help Table Viewer Postprocessing Postprocessing Row Filter RowID Column Resorter ChemistryExternal Tool Excel Reader (XLS)(deprecated) Configuration Postprocessing Row Filter Table Viewer Run Maestro CSV Writer

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To use this workflow in KNIME, download it from the below URL and open it in KNIME:

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Created by: bhola
Created at: 2017-07-27
On NodePit since: 2020-02-17
Last update: 2020-02-26
Created with KNIME version: v4.1.0
Tags: ProteinBioluminate

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