KNIME node to retrieve all generic kinase information from KLIFS optionally restricted to a user-supplied set of kinase IDs. This node returns a table comprising the KLIFS kinase ID, kinase name, HGNC symbol, kinase group, kinase family, kinase class, species, full name, UniProt accession code, IUPHAR ID, and the amino acid sequence of the pocket based on the KLIFS pocket definition using a consistent alignment of 85 residues. This information can, for example, be used to link KLIFS information to external resources (e.g. using HGNC symbols or UniProt, IUPHAR identifiers), to analyze pocket sequence identity/similarity, to associate kinase IDs with their kinases groups, families and classes, or to select kinases from a specific kinase class/family/group using a Row Filter (core KNIME node) to selectively retrieve KLIFS information.
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- Ligands Overview Retriever17 %
- Column Filter9 %
- Duplicate Row Filter8 %
- Kinase ID Mapper6 %
- Structures Overview Retriever6 %
- Row Filter6 %
- Joiner6 %
- Rule-based Row Filter6 %
- Structures Retriever4 %
- Structures PDB Mapper4 %
- Reference Row Filter4 %
Joiner4 %- Row Splitter3 %
- Fragment information1 %
- Kinase Information Retriever1 %
- Interaction Fingerprint Retriever1 %
Table Row To Variable Loop Start1 %CSV Writer1 %Cell Splitter1 %- GroupBy1 %
- String Manipulation1 %
- Value Counter1 %
- Excel Writer1 %
Python Script (1⇒1)1 %
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