Alphafold Database Search

This component is based on the AlphaFold Protein Structure Database (see: alphafold.ebi.ac.uk).
The Alphafold AI system predicts a protein's 3D structure from its amino acid sequence. The component uses an existing already trained version of Alphafold to predict the 3D structure.

The component provides a simple search against the database by entering a search term. As a result, the name/description, UniProt IDs, and organism from the search query will be displayed in a view as well as the 3D structure using the 3D Molecule Viewer component (Cartoon Style recommended). The results are available in the output table of the component, which also includes the UniProt Sequence.

For a simple search enter a protein name (e.g. fatty acid receptor), gene name (e.g. At1g58602), or Uniprot ID (e.g. Q5VSL9).


For more information see:

Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature (2021).

Varadi, M et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. Nucleic Acids Research (2021).

Options

Enter a search term.

Enter a query to search for a protein or gene.

Nodes

• Component Input3 ×
• Component Output3 ×
• Breakpoint2 ×
• Column Filter2 ×
• String Manipulation2 ×
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Extensions

• FeatureKNIME Base nodes
• FeatureKNIME Column Expressions (legacy)
• FeatureKNIME JavaScript Views
• FeatureKNIME Javasnippet
• FeatureKNIME JSON-Processing
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