IBIS Helmholtz-Node extension for KNIME Workbench version 184.108.40.206707071203 by IBIS KNIME Team
The MergeTwoVCFs node is based on the GATK CombineVariants tool.
It reads in variants records from two separate ROD (Reference-Ordered Data) sources and combines them into a single VCF.
This tool aims to fulfill two main possible use cases:
1.) It combines variant records present at the same site in the different input sources into a single variant record in the output.
2.) It assumes that each ROD source represents the same set of samples (although this is not enforced). It uses the priority list (if provided) to emit a single record instance at every position represented in the input RODs. This node can for example merge the output VCLs file from two different variant calling tools (e.g. Pindel and GATKHaplotypeCaller).
For further information, see GATK documentation of CombineVariants.
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