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Bioluminate 1

BioLuminate Residue Scanning

The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutation and evaluate the stability and affinity of the mutated structures. Additionally, you can gain access to the latest command-line only functionalities of the tool (e.g., to control Prime loop sampling options), run affinity maturation and aggregation calculations that can be used to compare the mutants.

[Requires: Bioluminate]

BioLuminate Residue Scanning: The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutation and evaluate the stability andaffinity of the mutated structures. Additionally, you can gain access to the latest command-line only functionalities of the tool (e.g., to control Prime loop samplingoptions), run affinity maturation and aggregation calculations that can be used to compare the mutants.[Requires: Bioluminate]Antibody/Antigen complexKeep chains H,L,WBioluminate Delta Affinity and stability Command line options Mutations H:103-105 Get PDB Protein PreparationWizard Delete Atoms Extract Properties Table Viewer Table Viewer Ungroup MAE Residue Scanning Get Help BioLuminate Residue Scanning: The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutation and evaluate the stability andaffinity of the mutated structures. Additionally, you can gain access to the latest command-line only functionalities of the tool (e.g., to control Prime loop samplingoptions), run affinity maturation and aggregation calculations that can be used to compare the mutants.[Requires: Bioluminate]Antibody/Antigen complexKeep chains H,L,WBioluminate Delta Affinity and stability Command line options Mutations H:103-105 Get PDB Protein PreparationWizard Delete Atoms Extract Properties Table Viewer Table Viewer Ungroup MAE Residue Scanning Get Help

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