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Onkopus Functional Variant Interpretation Basic(1)

Use Case 4: Protein data annotation- To annotate variant data at protein level (e.g. 'BRAF:V600E'), read in your data with a 'CSV-Reader' node and convert in to genomic level by adding a 'Protein_To_Genomic' node. You may then proceed with adding Onkopus annotation modules. BFrameto_VCFVCF-WriterVariantsVCF_to_BFrame (GRCh38)VCF-ReaderProtein_To_GenomicFunctionalregions(GENCODE)CSV-WriterVariantsBFrameto_CSVPathogenicityscoresProtein featuresPython Script CSV Writer Python Script File Reader Python Script Python Script CSV Writer Python Script Python Script Python Script Use Case 4: Protein data annotation- To annotate variant data at protein level (e.g. 'BRAF:V600E'), read in your data with a 'CSV-Reader' node and convert in to genomic level by adding a 'Protein_To_Genomic' node. You may then proceed with adding Onkopus annotation modules. BFrameto_VCFVCF-WriterVariantsVCF_to_BFrame (GRCh38)VCF-ReaderProtein_To_GenomicFunctionalregions(GENCODE)CSV-WriterVariantsBFrameto_CSVPathogenicityscoresProtein featuresPython Script CSV Writer Python Script File Reader Python Script Python Script CSV Writer Python Script Python Script Python Script

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To use this workflow in KNIME, download it from the below URL and open it in KNIME:

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Created by: nadine
Created at: 2024-07-22
On NodePit since: 2024-11-08
Last update: 2024-11-23
Created with KNIME version: v5.3.2

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