Icon

Onkopus Functional Variant Interpretation

Use Case 4: Protein data annotation- To annotate variant data at protein level (e.g. 'BRAF:V600E'), read in your data with a 'CSV-Reader' node and convert in to genomic level by adding a 'Protein_To_Genomic' node. You may then proceed with adding Onkopus annotation modules. CSV_to_BFrameCSV-ReaderCombinedatasetsVCF-ReaderProtein_To_GenomicFunctionalregions(GENCODE)BFrameto_CSVPathogenicityscoresProtein featuresVCF_to_BFrame (GRCh38)CSV-WriterVariantsPython Script File Reader Python Script File Reader Python Script Python Script Python Script Python Script Python Script Python Script CSV Writer Use Case 4: Protein data annotation- To annotate variant data at protein level (e.g. 'BRAF:V600E'), read in your data with a 'CSV-Reader' node and convert in to genomic level by adding a 'Protein_To_Genomic' node. You may then proceed with adding Onkopus annotation modules. CSV_to_BFrameCSV-ReaderCombinedatasetsVCF-ReaderProtein_To_GenomicFunctionalregions(GENCODE)BFrameto_CSVPathogenicityscoresProtein featuresVCF_to_BFrame (GRCh38)CSV-WriterVariantsPython Script File Reader Python Script File Reader Python Script Python Script Python Script Python Script Python Script Python Script CSV Writer

Nodes

Extensions

Links

Download

To use this workflow in KNIME, download it from the below URL and open it in KNIME:

Download Workflow
Created by: nadine
Created at: 2024-07-22
On NodePit since: 2024-10-02
Last update: 2024-11-23
Created with KNIME version: v5.3.2

Deploy, schedule, execute, and monitor your KNIME workflows locally, in the cloud or on-premises – with our brand new NodePit Runner.

Try NodePit Runner!