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Kaplan-Meier_​Time-to-Event_​Analysis

Kaplan-Meier Time-To-Event Analysis

This workflow shows how to do a time-to-event analysis using an ADaM* (in particular a ADTTE.xpt) dataset.
ADaM datasets are mainly stored in .xpt file format. For this, Lhasa Limited provides a dedicated node - the XPT Reader (Beta).
In order to create a Kaplan-Meier plot using the Kaplan-Meier Estimator node, the column containing the event informations needs to be converted into a boolean type with true and false values. For this the Column Expression node can be used.

When using the data provided under the Link below, the event is for example a dermatologic event. It could be also used for a survival analysis with a corresponding dataset.

*Analysis Data Model


This workflow snippet shows how to create a Kaplan-Meyer Plot that allows a time-to-event analysis of a certainevent from a clinical trial ADaM (Analysis Data Model) data set. The link to the data set can be found in the workflowdescription. The Kaplan-Meier Estimator expects a boolean columncontaining true and false values describing the occurence ofan event. Execute and Open Viewsto look into the plotUpload anadtte.xpt fileCreate a column with type booleanwith true/false values Kaplan-MeierEstimator XPT Reader (Beta) Column Expressions This workflow snippet shows how to create a Kaplan-Meyer Plot that allows a time-to-event analysis of a certainevent from a clinical trial ADaM (Analysis Data Model) data set. The link to the data set can be found in the workflowdescription. The Kaplan-Meier Estimator expects a boolean columncontaining true and false values describing the occurence ofan event. Execute and Open Viewsto look into the plotUpload anadtte.xpt fileCreate a column with type booleanwith true/false valuesKaplan-MeierEstimator XPT Reader (Beta) Column Expressions

Nodes

Extensions

Links

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To use this workflow in KNIME, download it from the below URL and open it in KNIME:

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Created by: Martyna
Created at: 2021-09-14
On NodePit since: 2021-12-18
Last update: 2024-12-26
Created with KNIME version: v4.4.1
Tags: Life SciencesADaMClinical TrialTime to Event

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