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Onkopus Clinical Variant Interpretation

Clinical variant interpretation Add a node 'Clinical evidence' to retrieve evidence-based data of possible treatments regarding the annotated variants. To manually select the clinical evidence databases, you may also manually add the modules 'CIViC', 'OncoKB' and 'MetaKB', followed by an 'Aggregator' module. MAF-WriterVariantsBFrameto_MAFPathogenicityscores (all)PopulationfrequencyProtein_annotation (SeqCAT)ProteinfeaturesExportTreatments (CSV)BFrameto_CSVExportVariants (CSV)VCF-ReaderTreatments_ExportVCF_to_BFrame (GRCh37)CSV-WriterVariantsBFrameto_CSVLiftOver (GRCh37 to GRCh38)VCF_to_BFrame (GRCh38)Clinical evidenceDrug classificationCSV Writer Python Script Python Script Python Script Python Script Python Script CSV Writer Python Script CSV Writer File Reader Python Script Python Script CSV Writer Python Script Python Script Python Script Python Script Python Script Clinical variant interpretation Add a node 'Clinical evidence' to retrieve evidence-based data of possible treatments regarding the annotated variants. To manually select the clinical evidence databases, you may also manually add the modules 'CIViC', 'OncoKB' and 'MetaKB', followed by an 'Aggregator' module. MAF-WriterVariantsBFrameto_MAFPathogenicityscores (all)PopulationfrequencyProtein_annotation (SeqCAT)ProteinfeaturesExportTreatments (CSV)BFrameto_CSVExportVariants (CSV)VCF-ReaderTreatments_ExportVCF_to_BFrame (GRCh37)CSV-WriterVariantsBFrameto_CSVLiftOver (GRCh37 to GRCh38)VCF_to_BFrame (GRCh38)Clinical evidenceDrug classificationCSV Writer Python Script Python Script Python Script Python Script Python Script CSV Writer Python Script CSV Writer File Reader Python Script Python Script CSV Writer Python Script Python Script Python Script Python Script Python Script

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Created by: nadine
Created at: 2024-07-22
On NodePit since: 2025-02-14
Last update: 2025-03-31
Created with KNIME version: v5.3.2

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