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MassSpectInKnime2 version 1.0.1

This node is useful for normalizing mass spectrometry intensities. It supports 3 methods of normalization.


This is the industry standard in normalization of MSI data, specifically, it calculates the Total Ion Count, ie the sum of the intensities. Then we divide each intensity in that spectrum by its TIC.
This method of normalization is simple and is gaining popularity in MSI. We simply calculate the median intensity for a spectrum. Then we divide each intensity value by this.
Euclidean Norm
This method of Normalization involves calculating the Euclidean Norm of the intensities of our Mass spectrometry data. Then we divide each intensity value by this.

Input Ports

The incoming data should contain rows of data that are to be independently normalized.

Output Ports

The outgoing data consists of the normalized incoming data.


To use this node in KNIME, download the below referenced file, save it to your KNIME's plugin folder and restart KNIME.


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