This workflow allows the user to select a disease from ChEMBL DB and perform a search of every target (single protein or protein complex) that has reports of (experimental or annotations) compounds or drugs related to the disease. Those targets are classified based on the phase of development of their compounds or drugs. Also a protein-protein interaction network is constructed via STRING API.
The results are two networks, full network and filtered by Open Targets Platform disease associated targets; and two lists of targets containing all targets and filtered by Open targets Platform with a score based in the types of target classification.
To use this workflow in KNIME, download it from the below URL and open it in KNIME:
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Please note that this is only about NodePit. We do not provide general support for KNIME — please use the KNIME forums instead.