0 ×

Bioluminate 1-2

Workflow

BioLuminate Residue Scanning: The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutationand evaluate the stability and affinity of the mutated structures. Additionally, you can gain access to the latest command-line onlyfunctionalities of the tool (e.g., to control Prime loop sampling options), run affinity maturation and aggregation calculations that can beused to compare the mutants.[Version: 2.8.0] [Requires: Bioluminate]Antibody/Antigen complexKeep chains H,L,WBioluminate profileCartoon ribbons colored by antibody structureAll - A(ction) > Preset > Antibody Antibody structure split into Fc, Fab and FvBioluminate Delta Affinity and stability Command line optionsSplit antibody Regions Mutations H:103-105 Get PDB Protein PreparationWizard Delete Atoms Run Maestro Ungroup MAE Run Maestro Extract Properties Table Viewer Table Viewer ChemistryExternal Tool Concatenate(Optional in) Table Viewer Ungroup MAE Residue Scanning Get Help BioLuminate Residue Scanning: The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutationand evaluate the stability and affinity of the mutated structures. Additionally, you can gain access to the latest command-line onlyfunctionalities of the tool (e.g., to control Prime loop sampling options), run affinity maturation and aggregation calculations that can beused to compare the mutants.[Version: 2.8.0] [Requires: Bioluminate]Antibody/Antigen complexKeep chains H,L,WBioluminate profileCartoon ribbons colored by antibody structureAll - A(ction) > Preset > Antibody Antibody structure split into Fc, Fab and FvBioluminate Delta Affinity and stability Command line optionsSplit antibody Regions Mutations H:103-105 Get PDB Protein PreparationWizard Delete Atoms Run Maestro Ungroup MAE Run Maestro Extract Properties Table Viewer Table Viewer ChemistryExternal Tool Concatenate(Optional in) Table Viewer Ungroup MAE Residue Scanning Get Help

Download

Get this workflow from the creator’s website: Link

Nodes

Bioluminate 1-2 consists of the following 15 nodes(s):

Plugins

Bioluminate 1-2 contains nodes provided by the following 2 plugin(s):